| 1 | Bahrain Grand Prix (history) | Bahrain International Circuit, Sakhir | 28 Mar 2021 | Done | Lewis Hamilton | Max Verstappen |
| 2 | Emilia Romagna Grand Prix (history) | Autodromo Enzo e Dino Ferrari, Imola | 18 Apr 2021 | Done | Max Verstappen | Lewis Hamilton |
| 3 | Portuguese Grand Prix (history) | Autódromo Internacional do Algarve, Portimão | 2 May 2021 | Done | Lewis Hamilton | Valtteri Bottas |
| 4 | Spanish Grand Prix (history) | Circuit de Barcelona-Catalunya, Montmeló | 9 May 2021 | Done | Lewis Hamilton | Lewis Hamilton |
| 5 | Monaco Grand Prix (history) | Circuit de Monaco, Monte-Carlo | 23 May 2021 | Done | Max Verstappen | Charles Leclerc |
| 6 | Azerbaijan Grand Prix (history) | Baku City Circuit, Baku | 6 Jun 2021 | Done | Sergio Perez | Charles Leclerc |
| 7 | French Grand Prix (history) | Circuit Paul Ricard, Le Castellet | 20 Jun 2021 | Done | Max Verstappen | Max Verstappen |
| 8 | Styrian Grand Prix (history) | Red Bull Ring, Spielberg | 27 Jun 2021 | Done | Max Verstappen | Max Verstappen |
| 9 | Austrian Grand Prix (history) | Red Bull Ring, Spielberg | 4 Jul 2021 | Done | Max Verstappen | Max Verstappen |
| 10 | British Grand Prix (history) | Silverstone Circuit, Silverstone | 18 Jul 2021 | Done | Lewis Hamilton | Max Verstappen |
| 11 | Hungarian Grand Prix (history) | Hungaroring, Budapest | 1 Aug 2021 | Done | Esteban Ocon | Lewis Hamilton |
| 12 | Belgian Grand Prix (history) | Circuit de Spa-Francorchamps, Spa | 29 Aug 2021 | Done | Max Verstappen | Max Verstappen |
| 13 | Dutch Grand Prix (history) | Circuit Park Zandvoort, Zandvoort | 5 Sep 2021 | Done | Max Verstappen | Max Verstappen |
| 14 | Italian Grand Prix (history) | Autodromo Nazionale di Monza, Monza | 12 Sep 2021 | Done | Daniel Ricciardo | Max Verstappen |
| 15 | Russian Grand Prix (history) | Sochi Autodrom, Sochi | 26 Sep 2021 | Done | Lewis Hamilton | Lando Norris |
| 16 | Turkish Grand Prix (history) | Istanbul Park, Istanbul | 10 Oct 2021 | Done | Valtteri Bottas | Valtteri Bottas |
| 17 | United States Grand Prix (history) | Circuit of the Americas, Austin | 24 Oct 2021 | Done | Max Verstappen | Max Verstappen |
| 18 | Mexico City Grand Prix (history) | Autódromo Hermanos Rodríguez, Mexico City | 7 Nov 2021 | Done | Max Verstappen | Valtteri Bottas |
| 19 | São Paulo Grand Prix (history) | Autódromo José Carlos Pace, São Paulo | 14 Nov 2021 | Done | Lewis Hamilton | Valtteri Bottas |
| 20 | Qatar Grand Prix (history) | Losail International Circuit, Al Daayen | 21 Nov 2021 | Done | Lewis Hamilton | Lewis Hamilton |
| 21 | Saudi Arabian Grand Prix (history) | Jeddah Corniche Circuit, Jeddah | 5 Dec 2021 | Done | Lewis Hamilton | Lewis Hamilton |
| 22 | Abu Dhabi Grand Prix (history) | Yas Marina Circuit, Abu Dhabi | 12 Dec 2021 | Done | Max Verstappen | Max Verstappen |